Understanding cognitive symptoms and future outlook in early Alzheimer's disease
Study of Cognitive Symptoms and Future Time Perspective in Preclinical Alzheimer's Disease
This study is looking at how people who have early signs of Alzheimer's, even though they feel fine right now, think about their memory and what the future might hold for them, especially after learning about their brain scan results; the goal is to understand how to better support them as they navigate this journey.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10851734 on NIH RePORTER |
What this research studies
This research investigates how individuals with preclinical Alzheimer's disease, who show no cognitive impairment but have biomarker evidence of the disease, experience cognitive symptoms and their perspective on the future. The study focuses on subjective cognitive complaints and how knowledge of their amyloid PET scan results influences these experiences. By examining these factors, the research aims to identify the psychological support needed for individuals as they transition from cognitive health to potential cognitive decline. The findings could help shape interventions to delay or slow the progression of Alzheimer's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults who are cognitively unimpaired but have biomarker evidence of preclinical Alzheimer's disease.
Not a fit: Patients who are already experiencing significant cognitive impairment or have a diagnosis of Alzheimer's disease will not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved psychological support and interventions for individuals at risk of developing Alzheimer's disease.
How similar studies have performed: Other research has shown promise in understanding cognitive symptoms in Alzheimer's disease, making this approach a continuation of established findings.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Stites, Shana D. — University of Pennsylvania
- Study coordinator: Stites, Shana D.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.