Understanding cognitive resilience in older Samoans

Cognitive Resilience among Older Samoans

NIH-funded research Yale University · NIH-11045078

This study is looking at why older Samoans seem to have less dementia than other groups, focusing on their positive views about aging and a special gene that might help keep their minds sharp, with the hope that what we learn can help older people everywhere.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-11045078 on NIH RePORTER

What this research studies

This research investigates why older Samoans experience lower rates of dementia compared to other populations. It focuses on cultural factors, such as positive beliefs about aging, and a specific genetic variant that may contribute to better cognitive health. The study will analyze memory scores and other cognitive measures among older Samoans to identify protective factors against dementia. By examining these elements, the research aims to uncover insights that could benefit aging populations globally.

Who could benefit from this research

Good fit: Ideal candidates for this research are older Samoans, particularly those living in Samoa or similar communities.

Not a fit: Patients who are not of Samoan descent or those who do not fall within the older age demographic may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for promoting cognitive health and resilience in older adults.

How similar studies have performed: Previous research has shown success in understanding cognitive resilience through cultural and genetic factors, but this specific focus on Samoans is novel.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions adult onset diabetesAdult-Onset Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.