Understanding cognitive outcomes in young survivors of medulloblastoma.
Official title: Outcomes in AYA survivors of pediatric medulloblastoma.
Funded at Emory University · NIH-11246676 · Data updated 2026-11-12
This study is looking at what affects thinking and learning in kids and young adults who have survived medulloblastoma, a type of brain tumor, to help understand why some have more trouble than others, and it's for those who have gone through this experience.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | July 5, 2022 |
| Project end | December 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $697,367 |
| NIH project number | 7R01CA261887-04 |
| Project ID | NIH-11246676 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are pediatric, adolescent, and young adult survivors of medulloblastoma who have undergone treatment.
✕Less likely to help
Patients who have not been diagnosed with medulloblastoma or who are not survivors of pediatric brain tumors may not benefit from this research.
What this research studies
This research investigates the factors influencing cognitive outcomes in pediatric, adolescent, and young adult survivors of medulloblastoma, a type of brain tumor. It aims to identify both clinical and environmental factors that contribute to cognitive impairment, which is common among these survivors. By examining genetic predispositions and various environmental resources, the study seeks to understand why some individuals experience severe cognitive issues while others do not. The research will be conducted across multiple cancer centers in Georgia, Alabama, and Ohio, providing a comprehensive analysis of these factors.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for monitoring and supporting cognitive health in young survivors of medulloblastoma.
How similar studies have gone: Previous research has shown that understanding the multifactorial influences on cognitive outcomes can lead to significant advancements in care for cancer survivors.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: King, Tricia Z. — Emory University
- Study coordinator: King, Tricia Z.
Related research
Other NIH-funded projects on the same topics.
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-
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A study using a pediatric brain cancer model to test how radiation-activated digoxin-like compounds could safely reach brain tumors in children.
-
Overcoming medulloblastoma resistance in kids using in vivo perturb-seq and preclinical therapies
A patient-focused study aiming to find new, less toxic ways to treat pediatric medulloblastoma by using advanced genetic screening to identify effective drug targets in preclinical models.
-
Dysregulation of a key gene complex and its role in Group 4 medulloblastoma
A study explores how disruption of a core gene complex in brain development may drive Group 4 medulloblastoma and seeks to understand new ways to help affected children.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.