Understanding cognitive issues in older adults with high parathyroid hormone levels
Characterizing neurocognitive symptoms in older adults with primary hyperparathyroidism
This study looks at how primary hyperparathyroidism might affect memory and thinking skills in older adults aged 65 and up, helping to show why it's important to diagnose and treat this condition for better brain health and overall quality of life.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-10725231 on NIH RePORTER |
What this research studies
This research investigates how primary hyperparathyroidism (PHPT) affects cognitive function in older adults aged 65 and above. It focuses on identifying neurocognitive symptoms, such as memory impairment and cognitive dysfunction, which may be the only signs of the condition in many patients. The study employs objective neurocognitive testing to assess the impact of PHPT on concentration and memory. By exploring these connections, the research aims to highlight the importance of diagnosing and treating PHPT to improve cognitive health and quality of life for older adults.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 65 and above who may be experiencing cognitive symptoms and have been diagnosed with primary hyperparathyroidism.
Not a fit: Patients who are younger than 65 or do not have primary hyperparathyroidism are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnosis and treatment of cognitive issues in older adults, ultimately improving their quality of life.
How similar studies have performed: Previous studies have shown that treating primary hyperparathyroidism can lead to significant improvements in cognitive function, indicating that this research builds on established findings.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Kazaure, Hadiza S — Duke University
- Study coordinator: Kazaure, Hadiza S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.