Understanding cognitive impairment and dementia after a stroke

Post-stroke Cognitive Impairment and Dementia

['FUNDING_R01'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-10943759

This study is looking at how strokes can lead to memory and thinking problems, especially in people who have had a stroke, and it aims to find out what factors might increase the risk and whether certain medications can help prevent these issues for stroke survivors.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUT SOUTHWESTERN MEDICAL CENTER (nih funded)
Locations1 site (DALLAS, UNITED STATES)
Trial IDNIH-10943759 on ClinicalTrials.gov

What this research studies

This research investigates how strokes contribute to cognitive impairment and dementia, focusing on the prevalence and risk factors associated with post-stroke cognitive impairment and dementia (PSCID). By utilizing a large national stroke registry and Medicare data, the study aims to identify the incidence of PSCID and explore how various vascular risk factors may influence its development. The research will also evaluate the potential effectiveness of medications in preventing PSCID among stroke survivors. This approach aims to provide insights that could lead to better prevention strategies for those affected.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals who have experienced a stroke and are at risk of developing cognitive impairment or dementia.

Not a fit: Patients who have not experienced a stroke or do not have any cognitive impairment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prevention strategies for cognitive impairment and dementia in stroke survivors.

How similar studies have performed: Previous research has shown that understanding vascular contributions to cognitive impairment can lead to significant advancements in treatment and prevention strategies.

Where this research is happening

DALLAS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Alzheimer disease dementia, Alzheimer syndrome, Alzheimer's Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.