Understanding cognitive differences in people at high risk for Alzheimer's disease
Cognitive heterogeneity in those with high Alzheimer's Disease Risk
This study is looking at how thinking skills differ in people who are at high risk for Alzheimer's disease but don't have symptoms yet, to help find ways to spot early signs of the disease and understand how it might develop.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-11060755 on NIH RePORTER |
What this research studies
This research investigates the cognitive differences among individuals who are at high risk for Alzheimer's disease (AD), particularly focusing on those who may not show symptoms yet. By analyzing data from blood samples, brain scans, and post-mortem tissue, the study aims to identify distinct cognitive profiles that can help predict who will progress to clinical stages of AD. The approach emphasizes a data-driven framework to improve early detection and understanding of cognitive changes associated with AD risk. Participants will undergo various assessments to determine their cognitive performance and risk levels.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals aged 65 and older who are identified as being at high risk for Alzheimer's disease.
Not a fit: Patients who are not at risk for Alzheimer's disease or those who are already experiencing advanced symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for early detection of Alzheimer's disease, allowing for timely interventions.
How similar studies have performed: Previous research has shown promise in identifying cognitive profiles related to Alzheimer's risk, suggesting that this approach may yield valuable insights.
Where this research is happening
Boston, United States
- Boston University Medical Campus — Boston, United States (Active)
Researchers
- Principal investigator: Au, Rhoda — Boston University Medical Campus
- Study coordinator: Au, Rhoda
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.