Understanding cognitive development in children with Down syndrome
Risk for Severe/Profound Intellectual Disability in Down Syndrome
['FUNDING_R01'] · COLORADO STATE UNIVERSITY · NIH-10780464
This study is looking at how children with Down syndrome, especially those with more severe intellectual challenges, grow and learn over time, and it aims to find out what helps or hinders their cognitive development, so we can better understand their unique abilities.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | COLORADO STATE UNIVERSITY (nih funded) |
| Locations | 1 site (FORT COLLINS, UNITED STATES) |
| Trial ID | NIH-10780464 on ClinicalTrials.gov |
What this research studies
This research investigates the cognitive outcomes of children with Down syndrome, focusing on those who experience severe or profound intellectual disability. The study aims to identify early cognitive growth patterns and the factors that contribute to significant cognitive delays. Researchers will assess 90 children at different stages of development, collecting blood samples and behavioral data to explore the relationship between cognitive abilities and biological markers. The goal is to enhance understanding of the variability in cognitive skills among children with Down syndrome.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-3 years diagnosed with Down syndrome.
Not a fit: Patients who are older than 3 years or do not have a diagnosis of Down syndrome may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved early interventions and support strategies for children with Down syndrome who are at risk for severe cognitive delays.
How similar studies have performed: Previous research has shown success in understanding cognitive development in Down syndrome, but this specific focus on severe/profound intellectual disability is relatively novel.
Where this research is happening
FORT COLLINS, UNITED STATES
- COLORADO STATE UNIVERSITY — FORT COLLINS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FIDLER, DEBORAH J — COLORADO STATE UNIVERSITY
- Study coordinator: FIDLER, DEBORAH J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autistic Disorder