Understanding cognitive decline in people with pre-diabetes and type 2 diabetes
Cognitive impairment in the DPPOS cohort and its neuropathologic, neurophysiologic, sociodemographic, and behavioral correlates
This study is looking at how conditions like mild cognitive impairment and dementia might be linked to pre-diabetes and type 2 diabetes, and it’s for people who want to understand how their brain health and diabetes might be connected.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10924055 on NIH RePORTER |
What this research studies
This research investigates how cognitive decline, mild cognitive impairment (MCI), and dementia are related to pre-diabetes and type 2 diabetes in a large group of participants. It aims to explore various factors, including brain pathology, insulin regulation, and sociodemographic influences, that may contribute to cognitive issues in these populations. The study will involve measuring specific biomarkers in blood and conducting brain imaging to assess the health of participants' brains. By analyzing these factors, the research seeks to fill knowledge gaps about the connections between diabetes and cognitive health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with pre-diabetes or type 2 diabetes who may be experiencing cognitive decline.
Not a fit: Patients without pre-diabetes or type 2 diabetes, or those who do not have any cognitive impairment, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of cognitive impairment in individuals with pre-diabetes and type 2 diabetes.
How similar studies have performed: Previous research has shown associations between diabetes and cognitive impairment, but this study aims to explore these connections in a more detailed and comprehensive manner.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Noble, James Mccallum — Columbia University Health Sciences
- Study coordinator: Noble, James Mccallum
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.