Understanding cognitive changes in adults with HIV from birth

Immunologic Profiles of Distinct Cognitive Trajectories in Adultswith Perinatal HIV

['FUNDING_OTHER'] · UNIVERSITY OF WASHINGTON · NIH-10657484

This study is looking at how thinking skills change over time in adults who were born with HIV, and it aims to find out what helps keep their minds sharp by looking at their immune system and brain scans.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF WASHINGTON (nih funded)
Locations1 site (SEATTLE, UNITED STATES)
Trial IDNIH-10657484 on ClinicalTrials.gov

What this research studies

This research investigates how cognitive abilities change over time in adults who were born with HIV. It focuses on understanding the immune responses and biological markers that may protect against cognitive decline in this population. By studying a group of adults with perinatally acquired HIV in Connecticut, the research aims to identify factors that contribute to better cognitive outcomes. The approach includes evaluating cognitive performance alongside immune system markers and brain imaging to uncover potential neuroprotective mechanisms.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults who were born with HIV and are currently living with the condition.

Not a fit: Patients who acquired HIV later in life or those without cognitive impairment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for improving cognitive health in adults living with perinatally acquired HIV.

How similar studies have performed: While there has been some research on cognitive outcomes in adults with HIV, this specific focus on perinatally acquired HIV and its unique immune responses is relatively novel.

Where this research is happening

SEATTLE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.