Understanding cognitive challenges faced by breast cancer patients after chemotherapy
Translational Neuroscience Approaches to Cancer-Related Cognitive Impairment: Measurement, Mechanisms, and Function
This study is looking at how chemotherapy affects thinking and memory in breast cancer patients, and it aims to help improve care for those who experience these changes during and after treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10868728 on NIH RePORTER |
What this research studies
This research investigates cancer-related cognitive impairment (CRCI) experienced by breast cancer patients undergoing chemotherapy. It aims to identify the measurement, mechanisms, and functional impacts of CRCI through a nationwide cohort study. Patients will undergo cognitive testing before and after chemotherapy to assess changes in cognitive function, using specialized tests that are sensitive to brain function. The study seeks to provide insights into the long-term effects of chemotherapy on cognitive abilities, which could help improve patient care and support.
Who could benefit from this research
Good fit: Ideal candidates for this research are breast cancer patients who are about to undergo or have recently completed chemotherapy.
Not a fit: Patients who are not undergoing chemotherapy or those with pre-existing cognitive impairments unrelated to cancer treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of cognitive impairments in breast cancer patients, enhancing their quality of life.
How similar studies have performed: Other research has shown significant cognitive decline in cancer patients post-chemotherapy, indicating that this approach is based on established findings.
Where this research is happening
Rochester, United States
- University of Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Janelsins, Michelle C — University of Rochester
- Study coordinator: Janelsins, Michelle C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.