Understanding cognitive aging in breast cancer survivors
Official title: Cognitive aging in long-term breast cancer survivors
Funded at Sloan-Kettering Inst Can Research · NIH-10916199 · Data updated 2026-11-12
This study looks at how thinking skills change over time in breast cancer survivors aged 65 and older, comparing their experiences to those of people without cancer, to help understand their brain health many years after treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $696,066 |
| NIH project number | 5R01CA276265-02 |
| Project ID | NIH-10916199 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are breast cancer survivors aged 65 and older who were diagnosed between the ages of 55 and 60.
✕Less likely to help
Patients who are not breast cancer survivors or those younger than 65 years may not benefit from this research.
What this research studies
This research investigates how cognitive abilities change in breast cancer survivors who are 65 years and older, focusing on long-term outcomes 5 to 20 years after treatment. It compares the cognitive performance of these survivors with non-cancer controls across different age groups. The study employs online assessments and standard neuropsychological tests to evaluate cognitive function and examines the relationship between cognitive decline and factors like frailty and medical history. By tracking these changes over time, the research aims to provide insights into the cognitive health of older cancer survivors.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and support for cognitive health in older breast cancer survivors.
How similar studies have gone: Previous research has shown promising results in understanding cognitive changes in cancer survivors, but this study aims to explore long-term outcomes in a novel way.
Where this research is happening
-
Sloan-Kettering Inst Can Research
New York, United States Active
Researchers
- Principal investigator: Root, James C — Sloan-Kettering Inst Can Research
- Study coordinator: Root, James C
Related research
Other NIH-funded projects on the same topics.
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Cognitive aging in long-term breast cancer survivors
This research explores how aging affects thinking and memory in people who survived breast cancer many years after treatment, focusing on those 65 and older.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.