Understanding chronic lung diseases and their progression
Official title: The Penn LungMAP 3 team: Defining chronic lung disease
Funded at University of Pennsylvania · NIH-10975261 · Data updated 2026-11-12
This study is looking at different types of chronic lung diseases, like COPD and alpha-1 anti-trypsin deficiency, to understand how they work at a cellular level, and if you're a patient, you might be able to help by sharing tissue samples or taking part in assessments.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $798,727 |
| NIH project number | 1U01HL175409-01 |
| Project ID | NIH-10975261 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation include adults with Chronic Obstructive Pulmonary Disease (COPD), alpha-1 anti-trypsin deficiency, or other chronic lung diseases.
✕Less likely to help
Patients with acute lung conditions or those without chronic lung diseases may not benefit from this research.
What this research studies
This research focuses on chronic lung diseases, particularly Chronic Obstructive Pulmonary Disease (COPD) and alpha-1 anti-trypsin deficiency (A1AT). It aims to catalog the different types of lung disease phenotypes at a cellular level and identify molecular defects in the cells that contribute to these diseases. By utilizing advanced technologies, the research will explore how these diseases progress and develop new platforms to study them in detail. Patients may have the opportunity to contribute to this research through tissue samples or participation in clinical assessments.
Why it matters
Potential benefit: If successful, this research could lead to the development of novel therapies that improve the quality of life for patients with chronic lung diseases.
How similar studies have gone: Previous research has shown success in understanding chronic lung diseases through similar methodologies, indicating a promising avenue for further exploration.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Morrisey, Edward E — University of Pennsylvania
- Study coordinator: Morrisey, Edward E
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.