Understanding chronic low back pain caused by disc degeneration

Validation of a Translational Model of Chronic Discogenic Low Back Pain

NIH-funded research Arizona State University-Tempe Campus · NIH-10872767

This study is working on creating a new way to study chronic low back pain caused by disc problems in animals, which will help researchers understand the pain better and find new ways to help people like you who are dealing with this condition.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionArizona State University-Tempe Campus NIH-funded
Lab location1 site (Tempe, United States)
Project IDNIH-10872767 on NIH RePORTER

What this research studies

This research aims to develop and validate a new animal model that accurately mimics chronic low back pain associated with disc degeneration. By collaborating with experts in orthopedics and neuroscience, the project seeks to improve our understanding of the mechanisms behind this type of pain. The research involves reproducing a previously established rat model in a different laboratory to ensure its reliability and consistency. This could lead to better pain management strategies for patients suffering from chronic low back pain.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing chronic low back pain due to disc degeneration.

Not a fit: Patients with acute back pain or those whose pain is not related to disc degeneration may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment options for patients suffering from chronic low back pain.

How similar studies have performed: Other research has shown success in developing animal models for chronic pain, suggesting that this approach has potential for meaningful advancements.

Where this research is happening

Tempe, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.