Understanding chronic low back pain caused by disc degeneration
Official title: Validation of a Translational Model of Chronic Discogenic Low Back Pain
Funded at Arizona State University-Tempe Campus · NIH-10872767 · Data updated 2026-11-12
This study is working on creating a new way to study chronic low back pain caused by disc problems in animals, which will help researchers understand the pain better and find new ways to help people like you who are dealing with this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Arizona State University-Tempe Campus NIH-funded |
| Lab location | 1 site (Tempe, United States) |
| Project start | September 20, 2024 |
| Project end | February 28, 2026 |
| Funding year | 2024 |
| Award (this year) | $366,975 |
| NIH project number | 1R61NS133264-01A1 |
| Project ID | NIH-10872767 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals experiencing chronic low back pain due to disc degeneration.
✕Less likely to help
Patients with acute back pain or those whose pain is not related to disc degeneration may not benefit from this research.
What this research studies
This research aims to develop and validate a new animal model that accurately mimics chronic low back pain associated with disc degeneration. By collaborating with experts in orthopedics and neuroscience, the project seeks to improve our understanding of the mechanisms behind this type of pain. The research involves reproducing a previously established rat model in a different laboratory to ensure its reliability and consistency. This could lead to better pain management strategies for patients suffering from chronic low back pain.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for patients suffering from chronic low back pain.
How similar studies have gone: Other research has shown success in developing animal models for chronic pain, suggesting that this approach has potential for meaningful advancements.
Where this research is happening
-
Arizona State University-Tempe Campus
Tempe, United States Active
Researchers
- Principal investigator: Wachs, Rebecca Ann — Arizona State University-Tempe Campus
- Study coordinator: Wachs, Rebecca Ann
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.