Understanding chronic kidney disease in farming communities
Discovery Science Collaborative for CKDu
['FUNDING_U01'] · STANFORD UNIVERSITY · NIH-11163387
This project uses modern lab methods on health information and biological samples from people in affected farming areas to better understand why unexplained chronic kidney disease (CKDu) happens.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-11163387 on ClinicalTrials.gov |
What this research studies
You would be asked to share health information and biological samples while researchers collect clinical details at sites where CKDu is common. Labs at multiple institutions will analyze samples with genomics, transcriptomics, pathology, biomarker testing, physiology measures, and bioinformatics. Teams will compare results across different agricultural communities and look at links between acute kidney injury and longer-term CKDu. The effort also builds a shared data and lab infrastructure to support future research and possible interventions.
Who could benefit from this research
Good fit: Adults who live or work in CKDu-affected agricultural regions, including people with early or established CKD of unknown cause and those who have experienced acute kidney injury, would be the primary candidates.
Not a fit: People outside CKDu-endemic areas, those with kidney disease from known causes, or anyone seeking an immediate therapy are unlikely to get direct clinical benefit from participating.
Why it matters
Potential benefit: If successful, this work could identify causes, early warning markers, or targets that help prevent or better treat CKDu in affected communities.
How similar studies have performed: Prior regional research has suggested links to occupational and environmental factors but causes remain uncertain, and this multi-site molecular approach is newer and still unproven.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BHALLA, VIVEK — STANFORD UNIVERSITY
- Study coordinator: BHALLA, VIVEK
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.