Understanding Chronic Kidney Disease in African Americans
Multi-Omics and Chronic Kidney Disease: Correlation with Histology
['FUNDING_R01'] · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · NIH-11170648
This work looks closely at blood markers and kidney tissue to better understand why chronic kidney disease progresses differently in African Americans.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NEW YORK UNIVERSITY SCHOOL OF MEDICINE (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11170648 on ClinicalTrials.gov |
What this research studies
Many Americans develop chronic kidney disease (CKD), and the risk is especially high for African Americans, with current treatments often falling short. This project uses advanced methods to examine a wide range of biological information, like proteins and metabolites in the blood, and connects these findings to kidney health and tissue changes. By studying existing data from large groups of African Americans and expanding to a new group with kidney biopsies, we hope to find new ways to explain and address how CKD progresses. Our goal is to uncover specific markers and pathways that are important for understanding and treating this complex condition.
Who could benefit from this research
Good fit: This work is relevant to African Americans with chronic kidney disease, particularly those who have participated in studies like AASK or the Boston Kidney Biopsy Cohort Study.
Not a fit: Patients without chronic kidney disease or those not of African American descent may not directly benefit from the specific focus of this research.
Why it matters
Potential benefit: If successful, this work could lead to new ways to predict, prevent, and treat chronic kidney disease, especially for African Americans.
How similar studies have performed: The initial phase of this grant was highly productive, with many publications, and focused on confirming findings in multiple research and clinical groups.
Where this research is happening
NEW YORK, UNITED STATES
- NEW YORK UNIVERSITY SCHOOL OF MEDICINE — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GRAMS, MORGAN ERIKA — NEW YORK UNIVERSITY SCHOOL OF MEDICINE
- Study coordinator: GRAMS, MORGAN ERIKA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.