Understanding Chlamydia in men who have sex with women

The natural history of C. trachomatis urethral infections in men who have sex with women

NIH-funded research Indiana University Indianapolis · NIH-11132887

This project aims to understand how Chlamydia affects men and how their bodies fight off the infection, which could help prevent its spread to women.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionIndiana University Indianapolis NIH-funded
Lab location1 site (Indianapolis, United States)
Project IDNIH-11132887 on NIH RePORTER

What this research studies

Chlamydia is a common sexually transmitted infection that can cause serious health problems for women, but men often don't have symptoms and aren't routinely screened. This makes it hard to stop the infection from spreading. We want to learn if men can develop immunity to Chlamydia and identify factors that lead to reinfection, such as specific bacteria in the urethra or other STIs. By studying men who have been exposed to Chlamydia, we hope to find new ways to protect women from this infection.

Who could benefit from this research

Good fit: Ideal candidates for related future opportunities might include men who have been identified as contacts to women with confirmed Chlamydia infections.

Not a fit: Patients who do not have Chlamydia or are not at risk for sexually transmitted infections may not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could lead to better strategies for preventing Chlamydia reinfections in women and potentially new screening or treatment approaches for men.

How similar studies have performed: While Chlamydia screening programs have existed for decades, understanding immunity and reinfection patterns in men is a less explored area, making this approach novel.

Where this research is happening

Indianapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.