Understanding Chiari Malformation and its effects on brain development
Clinical Core
This study is looking for people with Chiari Malformation to join in and share their health experiences, so we can learn more about how this condition affects the brain and overall well-being, and help improve future treatments.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10876263 on NIH RePORTER |
What this research studies
This research focuses on Chiari Malformation (CM) and involves screening and enrolling participants to gather clinical data and neurobehavioral assessments. Patients will be recruited from Washington University and associated hospitals, and their health-related quality of life will be evaluated through various measures. The study aims to create a comprehensive registry and databases to support ongoing projects related to CM, including a clinical trial and genetic studies. By collecting and analyzing this data, the research seeks to better understand how CM affects brain development and neurological outcomes.
Who could benefit from this research
Good fit: Ideal candidates for participation include adolescents and adults diagnosed with Chiari Malformation.
Not a fit: Patients without a diagnosis of Chiari Malformation or related neurological conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for patients with Chiari Malformation.
How similar studies have performed: Previous research has shown success in similar approaches to understanding Chiari Malformation and its impacts, indicating a solid foundation for this study.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Limbrick, David Delmar — Washington University
- Study coordinator: Limbrick, David Delmar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.