Understanding cervical cancer in HIV-infected women after treatment
Project 2-Understanding CIN2+ among HIV infected women after LEEP: An epidemiological and immunohistochemical study
This study is looking at how living with HIV affects the chances of cervical problems coming back after women have had a special treatment for cervical changes, and it's especially for women in Kenya and Uganda who are dealing with these health challenges.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-10897815 on NIH RePORTER |
What this research studies
This research investigates the effects of cervical intraepithelial neoplasia (CIN2+) in women living with HIV who have undergone a specific treatment called loop electrosurgical excision procedure (LEEP). The study aims to understand how HIV impacts the persistence and recurrence of cervical abnormalities after treatment. By analyzing tissue samples and patient data, researchers will explore the relationship between HIV status and cervical cancer outcomes. This research is particularly focused on women in Kenya and Uganda, where cervical cancer is a significant health issue.
Who could benefit from this research
Good fit: Ideal candidates for this research are HIV-infected women who have undergone LEEP for cervical intraepithelial neoplasia.
Not a fit: Patients who are not HIV-infected or who have not undergone LEEP may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and better health outcomes for HIV-infected women at risk of cervical cancer.
How similar studies have performed: Previous studies have shown that HIV-infected women are at a higher risk for cervical cancer, indicating that this research addresses a critical and previously identified health concern.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Orango, Elkanah Omenge — Indiana University Indianapolis
- Study coordinator: Orango, Elkanah Omenge
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.