Understanding cerebrospinal fluid flow in children with hydrocephalus
Assessing CSF flow dynamics in pediatric hemorrhagic hydrocephalus
['FUNDING_R01'] · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · NIH-11056058
This study is looking at how fluid in the brain moves in children with a condition called pediatric hemorrhagic hydrocephalus, which can happen after bleeding in the brain, to better understand how this affects their brain health and find better ways to help them.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-11056058 on ClinicalTrials.gov |
What this research studies
This research investigates how cerebrospinal fluid (CSF) flows in children suffering from pediatric hemorrhagic hydrocephalus, a condition that can arise from bleeding in the brain. The study aims to explore the relationship between CSF dynamics and neuroinflammation, which may contribute to worsening brain injury in affected infants. Using a novel imaging technique called fluorescence cap-based transcranial optical tomography (fCTOT), researchers will analyze how CSF moves and how it relates to the health of the brain. The goal is to improve treatment strategies for this serious condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are infants under 11 years old diagnosed with pediatric hemorrhagic hydrocephalus.
Not a fit: Patients who are older than 11 years or do not have hydrocephalus may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better treatment options and outcomes for infants suffering from hydrocephalus.
How similar studies have performed: Previous research has shown promising results in understanding CSF dynamics and neuroinflammation, suggesting that this approach may yield valuable insights.
Where this research is happening
HOUSTON, UNITED STATES
- UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SEVICK, EVA M. — UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
- Study coordinator: SEVICK, EVA M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired brain injury