Understanding Cell Structures for Disease Treatment
Cell and Chemical Biology of Microtubules
['FUNDING_OTHER'] · HARVARD MEDICAL SCHOOL · NIH-11076200
This work explores how tiny structures inside our cells, called microtubules, are organized and function, aiming to find new ways to treat diseases like cancer and neurodegeneration.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | HARVARD MEDICAL SCHOOL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-11076200 on ClinicalTrials.gov |
What this research studies
Our cells rely on tiny structures called microtubules for organization, especially during cell division and in nerve cells. We are using advanced tools like microscopy, biochemistry, and genetics to understand how these microtubules work. By studying how cells divide, we hope to learn more about mistakes that can lead to birth defects and cancer. We are also looking for new drugs that could specifically target cancer cells without harming healthy ones, and investigating how microtubules get damaged in conditions like inflammation, cancer, and neurodegenerative diseases.
Who could benefit from this research
Good fit: This foundational research does not directly involve patient participation at this stage, but future clinical trials stemming from this work would seek patients with specific cancers or neurodegenerative diseases.
Not a fit: Patients without conditions related to cell division errors, cancer, or neurodegeneration would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new treatments for various cancers, birth defects, and neurodegenerative conditions by targeting fundamental cell processes.
How similar studies have performed: While the fundamental role of microtubules in cell biology is well-established, this research aims to uncover novel mechanisms and drug targets, building on existing knowledge but exploring new avenues.
Where this research is happening
BOSTON, UNITED STATES
- HARVARD MEDICAL SCHOOL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MITCHISON, TIMOTHY J — HARVARD MEDICAL SCHOOL
- Study coordinator: MITCHISON, TIMOTHY J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cancer Treatment, Cancers