Understanding Cell Signals Inside the Body's Cells
Investigation of a Newly Discovered Organelle-Based Signaling Paradigm
This research explores how cells communicate by looking at signals happening deep inside them, not just on their surface, to better understand diseases and how medicines work.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11088176 on NIH RePORTER |
What this research studies
For a long time, we thought cells only received signals on their outer surface, which then told them what to do. This project suggests that cells also have important communication happening inside, within tiny structures like endosomes and Golgi membranes. Researchers are using new tools to see how these internal signals work and how they affect a cell's response to outside messages. This deeper understanding could reveal why some medicines are effective and how they might be improved.
Who could benefit from this research
Good fit: This foundational research is not directly recruiting patients but aims to benefit anyone affected by diseases involving cell communication and drug action.
Not a fit: Patients seeking immediate new treatments or direct clinical intervention will not find direct benefit from this basic science project.
Why it matters
Potential benefit: This work could lead to new ways of thinking about how diseases develop and how to design more effective drugs by targeting internal cell communication.
How similar studies have performed: This project uses novel tools and challenges long-held beliefs about cell signaling, indicating a new and untested approach.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Irannejad, Roshanak — University of California, San Francisco
- Study coordinator: Irannejad, Roshanak
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.