Understanding cell metabolism at a single cell level using advanced techniques
Nanoelectrochemistry and Single Cell Metabolomics
['FUNDING_OTHER'] · PURDUE UNIVERSITY · NIH-10911886
This study is looking at how tiny molecules inside individual cells can help us understand human diseases better, using special tools that measure these molecules without disturbing the cells too much.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | PURDUE UNIVERSITY (nih funded) |
| Locations | 1 site (WEST LAFAYETTE, UNITED STATES) |
| Trial ID | NIH-10911886 on ClinicalTrials.gov |
What this research studies
This research focuses on exploring the differences in metabolite profiles at the single cell level to better understand human diseases. By utilizing nanoelectrochemical measurements, the study aims to quantify small molecule metabolites within cells while minimizing any disruption to their natural state. This innovative approach seeks to improve the accuracy of cellular metabolite measurements, which could lead to significant insights into various diseases. The research employs novel techniques like open circuit potentiometry to ensure minimal perturbation during measurements.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with diseases that exhibit significant cellular heterogeneity and metabolic dysfunction.
Not a fit: Patients with stable, well-understood conditions that do not involve significant cellular metabolic changes may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and treatments for a wide range of diseases by providing deeper insights into cellular metabolism.
How similar studies have performed: Other research has shown promising results using nanoelectrochemical techniques for cellular analysis, indicating potential success for this approach.
Where this research is happening
WEST LAFAYETTE, UNITED STATES
- PURDUE UNIVERSITY — WEST LAFAYETTE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DICK, JEFFREY E — PURDUE UNIVERSITY
- Study coordinator: DICK, JEFFREY E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Disease