Understanding Cell Division in Cancer
Analysis of Centrosome Dynamics
This project explores how tiny parts of our cells, called centrosomes, control cell division and how problems with them might lead to cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11137657 on NIH RePORTER |
What this research studies
Our cells contain important structures called centrosomes that help them divide properly. In cancer, these centrosomes often don't work right, which can cause cells to divide incorrectly and lead to tumor growth. This work aims to understand exactly how centrosomes manage cell division and what goes wrong in cancer cells. By learning more about these processes, we hope to find new ways to stop cancer cells from growing and spreading.
Who could benefit from this research
Good fit: Patients with various types of cancer could potentially benefit from future therapies developed based on the fundamental insights gained from this research.
Not a fit: Patients seeking immediate treatment options may not directly benefit from this foundational research, as it focuses on basic biological mechanisms.
Why it matters
Potential benefit: If successful, this work could lead to new strategies for developing cancer treatments that target how cancer cells divide.
How similar studies have performed: There is existing interest in developing cancer therapies that target centrosomes, suggesting this research builds upon a recognized area of importance.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Oegema, Karen F — University of California, San Diego
- Study coordinator: Oegema, Karen F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.