Understanding Cell Communication through Eph Receptors
Molecular mechanisms of Eph receptor signaling
This research explores how cells communicate using special proteins called Eph receptors, which is key to understanding conditions like cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-11137076 on NIH RePORTER |
What this research studies
This project aims to understand how cells communicate by studying how certain proteins, called Eph receptors, work. These receptors are like tiny antennas on cell surfaces that receive signals and trigger responses inside the cell. When these receptors don't work correctly, it can contribute to diseases such as cancer. Researchers are using advanced tools like special microscopes and genetic editing to precisely observe and understand these communication processes in human cells. By uncovering these fundamental mechanisms, we hope to find new ways to address diseases where cell communication goes wrong.
Who could benefit from this research
Good fit: This foundational research does not directly involve patient participation, but future clinical applications could benefit patients with various cancers or neurodegenerative conditions.
Not a fit: Patients seeking immediate treatment options would not directly benefit from this basic science research.
Why it matters
Potential benefit: If successful, this work could lead to new insights into how diseases like cancer develop and potentially inspire new treatment strategies.
How similar studies have performed: While the general concept of cell communication is well-established, this project uses cutting-edge techniques to explore the specific mechanisms of Eph receptor activation, which are currently not fully understood.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Belyy, Vladislav — Ohio State University
- Study coordinator: Belyy, Vladislav
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.