Understanding Cell Communication in Health and Disease
Chemical Approaches for Interrogating Fundamental Biomedical Processes
['FUNDING_OTHER'] · UNIVERSITY OF VIRGINIA · NIH-11129783
This project aims to understand how cells communicate using tiny signals and activities, which can go wrong in human diseases.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF VIRGINIA (nih funded) |
| Locations | 1 site (CHARLOTTESVILLE, UNITED STATES) |
| Trial ID | NIH-11129783 on ClinicalTrials.gov |
What this research studies
Our cells rely on complex communication systems involving small molecules and enzymes to function properly. When these systems don't work as they should, it can lead to various human diseases. This project uses specially designed fluorescent tools and protein systems to get a very detailed look at how these cellular signals work in both healthy and diseased cells. By observing these processes, we hope to gain a deeper understanding of what goes wrong at a molecular level. This knowledge is crucial for finding new ways to address diseases caused by faulty cell communication.
Who could benefit from this research
Good fit: This foundational work does not involve direct patient participation but aims to benefit individuals affected by diseases linked to abnormal cellular function.
Not a fit: Patients seeking immediate treatment options would not directly benefit from this basic science project.
Why it matters
Potential benefit: A deeper understanding of how cellular communication goes wrong in disease could lead to the development of new diagnostic tools and treatments.
How similar studies have performed: The research team has previously developed successful fluorescent probes and protein-based methods for controlling cellular signaling, indicating a strong foundation for this work.
Where this research is happening
CHARLOTTESVILLE, UNITED STATES
- UNIVERSITY OF VIRGINIA — CHARLOTTESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: STAINS, CLIFF I — UNIVERSITY OF VIRGINIA
- Study coordinator: STAINS, CLIFF I
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Disease