Understanding Cardiometabolic Disease in People
Human Translational Bioinformatics Core
This project uses advanced computer tools to understand how cardiometabolic diseases, like heart disease and diabetes, affect men and women differently by looking at information from many people.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-11168941 on NIH RePORTER |
What this research studies
Our bodies are complex, and conditions like heart disease and diabetes can affect men and women in unique ways. This project uses powerful computer analysis to connect discoveries made in lab models to real human health. We look at vast amounts of genetic, protein, and metabolic information from diverse groups of people to find clues about these diseases. The goal is to uncover why these conditions develop and progress differently between sexes, helping us move closer to personalized treatments.
Who could benefit from this research
Good fit: This project primarily involves analyzing existing human data, so direct patient participation is not expected, but future studies stemming from this work may seek individuals with cardiometabolic conditions.
Not a fit: Patients not interested in the genetic and biological underpinnings of cardiometabolic disease may not find direct benefit from this foundational research.
Why it matters
Potential benefit: If successful, this work could lead to a better understanding of cardiometabolic diseases and help develop more effective, sex-specific treatments.
How similar studies have performed: The lead researcher has successfully applied similar bioinformatics approaches in previous studies to understand cardiometabolic diseases using large human datasets.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Allayee, Hooman — University of California Los Angeles
- Study coordinator: Allayee, Hooman
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.