NIH-funded research R01 grant

Understanding cannabis use and cannabis use disorder in adults with chronic pain

Official title: Cannabis Use for Chronic Pain: Advancing Knowledge and Cannabis Use Disorder Assessment with a Mixed Methods Approach

Funded at Dartmouth College · NIH-11225957 · Data updated 2026-11-12

This project is creating clearer ways to tell when adult cannabis use for chronic pain is helpful versus when it becomes a cannabis use disorder.

More Chronic Pain research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDartmouth College
NIH-funded
Lab location1 site (Hanover, United States)
Project startSeptember 30, 2020
Project endJanuary 31, 2031
Funding year2026
Award (this year)$780,228
NIH project number2R01DA050032-06
Project IDNIH-11225957 on NIH RePORTER

Who could benefit from this research

Could help

Adults age 21 and older who use cannabis for chronic pain, whether medically authorized or not, are the most suitable candidates for this work.

Less likely to help

People under 21, those who do not use cannabis for pain, or those seeking immediate changes in pain treatment likely will not benefit directly from this project.

What this research studies

If you take part, researchers will ask adults about how and why they use cannabis for pain, including efforts to get medical authorization, dosing, and supervision. They will use interviews and online surveys and build on a new Cannabis Exposure Index (CEI) to measure actual use. The team will adapt a framework used for prescription opioids that separates therapeutic use from problematic use to see how it fits cannabis. Findings will be used to refine diagnostic questions and tools so clinicians can better understand patients' cannabis use.

Why it matters

Potential benefit: If successful, this work could help clinicians and patients distinguish therapeutic cannabis use from problematic use and guide safer cannabis practices for pain.

How similar studies have gone: The team previously developed the Cannabis Exposure Index and used opioid-based diagnostic models with good validity, but applying a therapeutic-use framework specifically to cannabis is relatively new.

Where this research is happening

  • Dartmouth College
    Hanover, United States
    Active

Researchers

  • Principal investigator: Borodovsky, Jacob T — Dartmouth College
  • Study coordinator: Borodovsky, Jacob T

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.