Understanding Cannabidiol for Cannabis Concentrate Users
Cannabidiol and Cannabis Concentrate Users: A Randomized, Placebo Controlled Study
This research explores if cannabidiol (CBD) can help reduce the effects and risks associated with using high-THC cannabis concentrates.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11124777 on NIH RePORTER |
What this research studies
Many cannabis products now have very high levels of THC, especially concentrates, which may lead to stronger effects and potential loss of control over use. We are looking into whether CBD, a non-intoxicating component of cannabis, can lessen these strong effects and reduce anxiety. Our approach involves a randomized, placebo-controlled comparison to see how different doses of plant-derived CBD affect frequent cannabis concentrate users. Participants will complete a four-week protocol, including sessions in a mobile pharmacology lab.
Who could benefit from this research
Good fit: Ideal candidates are adults aged 21 and older who frequently use cannabis concentrates.
Not a fit: Patients who do not use cannabis concentrates or are under 21 years old would not directly benefit from this particular research.
Why it matters
Potential benefit: If successful, this work could lead to new ways to help people manage their use of high-THC cannabis products and reduce associated risks.
How similar studies have performed: Preliminary data and several previous studies suggest that CBD may reduce cannabis use and the subjective response to THC.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Schacht, Joseph P. — University of Colorado Denver
- Study coordinator: Schacht, Joseph P.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.