Understanding Cancer's Genetic and Epigenetic Changes
Cancer Genetics and Epigenetics
This program at Johns Hopkins aims to understand how cancer starts and grows by looking closely at genetic and epigenetic changes, helping to develop more personalized care for patients.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11086177 on NIH RePORTER |
What this research studies
This program focuses on uncovering the genetic and epigenetic changes that drive individual human cancers, which are like the unique instruction sets within cancer cells. By understanding these changes at a very detailed level, researchers hope to learn how cancer begins and progresses. The findings from this work are then used to inform and develop new clinical trials and biomarker tests. The ultimate goal is to create personalized cancer care strategies tailored to each patient's specific cancer characteristics.
Who could benefit from this research
Good fit: Patients with various types of cancer who might benefit from future personalized treatment approaches based on their cancer's unique genetic and epigenetic makeup are the focus of this research.
Not a fit: Patients seeking immediate treatment options or those whose cancers do not involve genetic or epigenetic alterations relevant to this program's current focus may not directly benefit from this foundational research.
Why it matters
Potential benefit: If successful, this work could lead to more precise and effective personalized treatments for various cancers by targeting their unique genetic and epigenetic vulnerabilities.
How similar studies have performed: While this program explores novel aspects of cancer genetics and epigenetics, similar approaches in cancer research have shown promise in identifying new treatment targets and developing personalized therapies.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Azad, Nilofer S. — Johns Hopkins University
- Study coordinator: Azad, Nilofer S.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.