Understanding cancer through advanced protein and genetic analysis
Center of Excellence for High Throughput Proteogenomic Characterization
This study is looking at how proteins in cancer cells work and change, with the hope of finding new ways to help your body fight cancer and create personalized treatments just for you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Broad Institute, INC. NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-11119015 on NIH RePORTER |
What this research studies
This research focuses on cancer proteogenomics, which combines advanced techniques to measure proteins and their modifications with genetic data from cancer samples. By using state-of-the-art mass spectrometry and other technologies, the project aims to generate detailed profiles of proteins and metabolites in tumors. The goal is to uncover how cancer cells evade the immune system and to identify potential targets for personalized cancer therapies, including vaccines. Patients may benefit from insights that could lead to more effective treatments tailored to their specific cancer profiles.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with various types of cancer who are seeking innovative treatment options.
Not a fit: Patients with non-cancerous conditions or those not currently undergoing cancer treatment may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of personalized cancer therapies and vaccines that are more effective for individual patients.
How similar studies have performed: Previous research in cancer proteogenomics has shown promise in identifying new therapeutic targets and improving treatment outcomes, indicating that this approach has potential for success.
Where this research is happening
Cambridge, United States
- Broad Institute, INC. — Cambridge, United States (Active)
Researchers
- Principal investigator: Carr, Steven a — Broad Institute, INC.
- Study coordinator: Carr, Steven a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.