Understanding Cancer Proteins for Better Treatments
The Cancer Proteome Atlas: an Integrated Bioinformatics Resource for Functional Cancer Proteomic Data
This project is building a powerful online tool to help scientists better understand the proteins in cancer cells from patient samples, aiming to improve how we treat cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11159612 on NIH RePORTER |
What this research studies
This project focuses on improving a special online tool called The Cancer Proteome Atlas (TCPA), which helps scientists analyze protein information from cancer patients. Proteins are tiny building blocks in our cells that play a big role in how cancer grows and responds to medicine. By making this tool better, researchers can more easily look at many different proteins in thousands of cancer samples. This helps them find patterns and understand why some treatments work well for certain patients and not others. The goal is to make this information more accessible and useful for developing new and more effective cancer therapies.
Who could benefit from this research
Good fit: Patients whose tumor samples have been or will be analyzed using reverse-phase protein arrays (RPPAs) may indirectly benefit from the improved insights this resource provides.
Not a fit: Patients not affected by cancer or whose data is not part of the proteomic analyses would not directly benefit from this bioinformatics resource.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of cancer, helping doctors choose more effective treatments for individual patients and discover new drug targets.
How similar studies have performed: The existing Cancer Proteome Atlas (TCPA) has already been widely used by over 80,000 researchers, demonstrating the success of this approach in analyzing cancer proteomic data.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Liang, Han — University of Tx Md Anderson Can Ctr
- Study coordinator: Liang, Han
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.