Understanding Campylobacter to better control infections in developing countries
Genomic Epidemiology of Campylobacter to Improve Disease Control in Low and Middle Income Countries
This study is looking at the genes of Campylobacter, a common cause of infections, to understand where it comes from and why some strains resist treatment, with the hope of finding better ways to prevent infections and their complications, like Guillain-Barré syndrome, especially for people in low and middle-income countries.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project ID | NIH-11074097 on NIH RePORTER |
What this research studies
This research investigates the genetic factors of Campylobacter, a leading cause of bacterial infections, particularly in low and middle-income countries. By analyzing the genomes of Campylobacter strains, the study aims to identify the sources of infection and the mechanisms behind antimicrobial resistance. The goal is to develop targeted interventions that can effectively reduce the incidence of infections and related complications, such as Guillain-Barré syndrome. Patients may benefit from improved disease control measures based on the findings of this research.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living in low and middle-income countries who are at risk of Campylobacter infections.
Not a fit: Patients living in high-income countries or those not affected by Campylobacter infections may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective strategies for controlling Campylobacter infections, ultimately reducing illness and improving health outcomes for affected populations.
How similar studies have performed: Previous genomic epidemiology efforts in Europe have successfully informed interventions to reduce Campylobacter infections, indicating that similar approaches may be effective in other regions.
Where this research is happening
Charlottesville, United States
- University of Virginia — Charlottesville, United States (Active)
Researchers
- Principal investigator: Kosek, Margaret N — University of Virginia
- Study coordinator: Kosek, Margaret N
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.