Understanding calcium metabolism's role in lung cancer development
Official title: Calcium metabolism and lung cancer preneoplasia
Funded at University of Tx Md Anderson Can Ctr · NIH-11005320 · Data updated 2026-11-12
This study is looking at how calcium in the body might influence the growth of lung cancer cells, and it's for anyone interested in understanding more about lung cancer and finding new ways to treat it.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | January 1, 2024 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $81,000 |
| NIH project number | 5R03CA279867-02 |
| Project ID | NIH-11005320 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk for lung cancer or those with early-stage lung cancer.
✕Less likely to help
Patients with advanced lung cancer who have already undergone extensive treatment may not benefit from this research.
What this research studies
This research investigates how calcium metabolism affects the development of lung cancer, particularly focusing on the mechanisms that lead to abnormal cell proliferation. By using genetically engineered animal models, the study aims to uncover the role of the DREAM complex in regulating cell cycles and how its dysregulation contributes to lung tumorigenesis. The researchers will explore the interactions between calcium signaling and cancer biology to identify potential therapeutic targets for lung cancer treatment.
Why it matters
Potential benefit: If successful, this research could lead to new treatment strategies for lung cancer, improving outcomes for patients.
How similar studies have gone: Other research has shown promising results in targeting calcium signaling pathways in cancer treatment, suggesting that this approach may be effective.
Where this research is happening
-
University of Tx Md Anderson Can Ctr
Houston, United States Active
Researchers
- Principal investigator: Park, Jae-Il — University of Tx Md Anderson Can Ctr
- Study coordinator: Park, Jae-Il
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.