Understanding breathing difficulties in premature babies with lung disease
Calculating the Components of Work of Breathing in Neonates with Bronchopulmonary Dysplasia
['FUNDING_R01'] · CINCINNATI CHILDRENS HOSP MED CTR · NIH-10858162
This study is looking at babies who were born early and have breathing problems called bronchopulmonary dysplasia (BPD), and it aims to create a helpful tool that will figure out how their lungs work so doctors can give them the best care for their specific breathing needs.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CINCINNATI CHILDRENS HOSP MED CTR (nih funded) |
| Locations | 1 site (CINCINNATI, UNITED STATES) |
| Trial ID | NIH-10858162 on ClinicalTrials.gov |
What this research studies
This research focuses on neonates who have survived premature birth but are affected by bronchopulmonary dysplasia (BPD), a chronic lung condition. The project aims to develop a tool that calculates how different lung characteristics contribute to the effort required for breathing. By identifying specific phenotypes of BPD, the research will help tailor treatments to individual patients based on their unique breathing challenges. This approach seeks to improve the management of breathing difficulties in these vulnerable infants.
Who could benefit from this research
Good fit: Ideal candidates for this research are neonates diagnosed with bronchopulmonary dysplasia, particularly those who were born prematurely.
Not a fit: Patients who do not have bronchopulmonary dysplasia or who are older than 21 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatments for premature infants suffering from bronchopulmonary dysplasia.
How similar studies have performed: While the approach of calculating work of breathing in neonates is innovative, similar methodologies have shown promise in other respiratory conditions, suggesting potential for success.
Where this research is happening
CINCINNATI, UNITED STATES
- CINCINNATI CHILDRENS HOSP MED CTR — CINCINNATI, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BATES, ALISTER — CINCINNATI CHILDRENS HOSP MED CTR
- Study coordinator: BATES, ALISTER
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.