Understanding breast cancer progression in women of African ancestry
Etiology and Genomics of Breast Cancer Progression in Women of African Ancestry
This study is looking at the genetic reasons behind aggressive breast cancer in young women of African descent by examining tumor samples from Nigeria, with the goal of finding clues that could help improve treatment and understanding of this type of cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10610884 on NIH RePORTER |
What this research studies
This research investigates the genetic factors contributing to aggressive breast cancer in young women of African ancestry. By analyzing tumor samples from Nigeria, the study aims to identify specific genomic signatures that may drive tumor progression and influence treatment outcomes. The researchers will conduct whole-genome and whole-exome sequencing to uncover mutation patterns and their associations with risk factors. This comprehensive genomic analysis seeks to improve understanding of breast cancer disparities and inform targeted interventions.
Who could benefit from this research
Good fit: Ideal candidates for this research are young women of African ancestry diagnosed with breast cancer.
Not a fit: Patients who do not have breast cancer or are not of African ancestry may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and outcomes for women of African ancestry affected by breast cancer.
How similar studies have performed: Previous research has shown promising results in understanding cancer genomics, particularly in diverse populations, indicating potential for success in this novel approach.
Where this research is happening
Chicago, United States
- University of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Olopade, Olufunmilayo F. — University of Chicago
- Study coordinator: Olopade, Olufunmilayo F.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.