Understanding breast cancer metastasis in patients of African descent
Characterization of metastasis models derived from breast cancer patients of African descent
This study is looking at triple-negative breast cancer, especially in people of African descent, to understand how it spreads and find new treatment options that could work better for them.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Virginia Commonwealth University NIH-funded |
| Lab location | 1 site (Richmond, United States) |
| Project ID | NIH-10669268 on NIH RePORTER |
What this research studies
This research focuses on breast cancer, particularly triple-negative breast cancer (TNBC), which is more prevalent in individuals of African descent. The project aims to develop models that track how these cancers spread and to identify unique genetic factors that may influence treatment outcomes. By creating patient-derived models, the research will explore new therapeutic options that could be more effective for this population. The ultimate goal is to improve treatment strategies and outcomes for patients with TNBC.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals of African descent diagnosed with triple-negative breast cancer.
Not a fit: Patients with non-triple-negative breast cancer or those not of African descent may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments specifically tailored for breast cancer patients of African descent.
How similar studies have performed: While there has been research on breast cancer, this specific focus on African descent and the development of tailored metastasis models is relatively novel.
Where this research is happening
Richmond, United States
- Virginia Commonwealth University — Richmond, United States (Active)
Researchers
- Principal investigator: Harrell, Joshua (Chuck) — Virginia Commonwealth University
- Study coordinator: Harrell, Joshua (Chuck)
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.