Understanding brain tumors and their interactions with surrounding cells
Official title: Administrative Core
Funded at Massachusetts Institute of Technology · NIH-10930066 · Data updated 2026-11-12
This study is looking at how brain tumor cells interact with nearby brain cells and immune cells to understand how these relationships affect tumor growth and treatment success, with the hope of finding new ways to help people with aggressive brain tumors like glioblastoma.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts Institute of Technology NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project start | September 15, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $324,267 |
| NIH project number | 5U54CA283114-02 |
| Project ID | NIH-10930066 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with glioblastoma or other aggressive brain tumors.
✕Less likely to help
Patients with non-cancerous brain conditions or those with early-stage brain tumors may not benefit from this research.
What this research studies
This research focuses on the complex relationships between brain tumor cells and their surrounding environment, including neurons and immune cells. By using advanced systems biology techniques, the project aims to analyze how these interactions influence tumor growth and resistance to treatment. The goal is to identify new therapeutic strategies that can effectively target and disrupt these relationships, potentially leading to better outcomes for patients with aggressive brain tumors like glioblastoma.
Why it matters
Potential benefit: If successful, this research could lead to innovative treatments that improve survival rates and quality of life for patients with brain tumors.
How similar studies have gone: Previous research has shown promise in understanding tumor microenvironments, suggesting that this approach could lead to significant advancements in treatment.
Where this research is happening
-
Massachusetts Institute of Technology
Cambridge, United States Active
Researchers
- Principal investigator: White, Forest M — Massachusetts Institute of Technology
- Study coordinator: White, Forest M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.