Understanding brain tissue properties using advanced imaging techniques
Official title: Multiscale brain tissue finite element mechanical modeling to infer brain microstructural properties from magnetic resonance elastography
Funded at U.s. National Inst/child Hlth/human Dev · NIH-10712001 · Data updated 2026-11-12
This study is looking at how the stiffness of brain tissue can give us clues about brain health and diseases, using a special imaging technique to help create better ways to diagnose brain conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | U.s. National Inst/child Hlth/human Dev NIH-funded |
| Lab location | 1 site (Bethesda, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2023 |
| NIH project number | 1FI2GM150429-01 |
| Project ID | NIH-10712001 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with neurological conditions or those at risk for brain diseases, as well as healthy volunteers for comparison.
✕Less likely to help
Patients with acute brain injuries or those who are unable to undergo MRI procedures may not benefit from this research.
What this research studies
This research investigates how the mechanical properties of brain tissue relate to brain health and disease. By using a technique called magnetic resonance elastography (MRE), the study aims to measure the rigidity of brain tissue, which can indicate various health conditions. The researchers will develop detailed mechanical models of brain tissue that take into account both solid and fluid components, allowing them to better understand how these properties affect brain function. This approach could lead to improved diagnostic methods for brain-related conditions.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools for assessing brain health and detecting diseases earlier.
How similar studies have gone: Other studies using similar imaging techniques have shown promise in understanding brain mechanics, suggesting that this approach could yield valuable insights.
Where this research is happening
-
U.s. National Inst/child Hlth/human Dev
Bethesda, United States Active
Researchers
- Principal investigator: Rey, Julian Alejandro — U.s. National Inst/child Hlth/human Dev
- Study coordinator: Rey, Julian Alejandro
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.