Understanding brain tissue changes in Alzheimer's disease and related dementias
Neuropathology Core
This study is looking at brain tissue from people who had dementia, especially Alzheimer's, to find out more about the disease and how it affects the brain, which can help doctors and researchers better understand and treat it.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-10873083 on NIH RePORTER |
What this research studies
The Neuropathology Core (NPC) focuses on diagnosing brain tissue obtained from autopsies of patients with dementia, particularly Alzheimer's disease. By analyzing these tissues, the NPC aims to identify abnormal proteins and their locations in the brain, which can help in understanding the disease's progression and effects. The research also integrates genetic information to provide a more comprehensive view of the disease's causes and variations. This multidisciplinary approach not only aids in accurate diagnosis but also supports ongoing education for healthcare professionals and researchers about advancements in dementia research.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or related dementias who are willing to participate in autopsy procedures.
Not a fit: Patients who are not diagnosed with dementia or those who do not consent to autopsy procedures may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic methods and a better understanding of Alzheimer's disease, ultimately enhancing patient care and treatment options.
How similar studies have performed: Previous research has shown success in using similar neuropathological approaches to enhance understanding of Alzheimer's disease and improve diagnostic accuracy.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Ghetti, Bernardino Francesco — Indiana University Indianapolis
- Study coordinator: Ghetti, Bernardino Francesco
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.