Understanding brain signals related to aging and Alzheimer's Disease
fMRI physiological signatures of aging and Alzheimer's Disease
['FUNDING_OTHER'] · VANDERBILT UNIVERSITY · NIH-10361105
This study is looking at how signals from your heart and lungs can influence brain activity, especially as we age or in conditions like Alzheimer's Disease, and it aims to use this information to better understand brain health, with the help of patients who can provide valuable data.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VANDERBILT UNIVERSITY (nih funded) |
| Locations | 1 site (Nashville, UNITED STATES) |
| Trial ID | NIH-10361105 on ClinicalTrials.gov |
What this research studies
This research investigates how physiological signals from the heart and lungs affect brain activity as observed through functional magnetic resonance imaging (fMRI). By analyzing large datasets, the study aims to uncover how these signals relate to brain networks and cognitive functions, particularly in aging and Alzheimer's Disease. The researchers will develop new methods to extract important physiological information from existing fMRI data, which could enhance our understanding of brain health and disease. Patients may be involved in providing data that helps establish these critical connections.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults aged 21 and older, particularly those experiencing cognitive changes or diagnosed with Alzheimer's Disease.
Not a fit: Patients who are younger than 21 or do not have any cognitive impairments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and potentially new approaches for diagnosing and treating Alzheimer's Disease.
How similar studies have performed: Previous research has shown promise in using fMRI to study brain function, but this approach of integrating physiological data is relatively novel.
Where this research is happening
Nashville, UNITED STATES
- VANDERBILT UNIVERSITY — Nashville, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHANG, CATHERINE ELIZABETH — VANDERBILT UNIVERSITY
- Study coordinator: CHANG, CATHERINE ELIZABETH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer's Disease, Alzheimer disease, Alzheimer syndrome