Understanding Brain Signals in Movement Disorders
Role of KCTD proteins in striatal signaling
['FUNDING_R01'] · AUGUSTA UNIVERSITY · NIH-11127678
This project aims to better understand how certain proteins affect brain signals related to movement disorders.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | AUGUSTA UNIVERSITY (nih funded) |
| Locations | 1 site (AUGUSTA, UNITED STATES) |
| Trial ID | NIH-11127678 on ClinicalTrials.gov |
What this research studies
Movement disorders are a growing health concern, and current treatments are limited because we don't fully understand the brain's signaling pathways. This project focuses on how specific proteins, called KCTD proteins, influence a key signaling pathway in the brain called cAMP. Researchers will explore how these proteins interact with other brain signals, including zinc, to control movement. By uncovering these detailed mechanisms, we hope to find new ways to approach these challenging conditions.
Who could benefit from this research
Good fit: Patients with movement disorders may eventually benefit from the new insights gained from this fundamental research.
Not a fit: Patients seeking immediate new treatments will not directly benefit from this basic science project.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of movement disorders, paving the way for more effective treatment strategies in the future.
How similar studies have performed: While KCTD proteins have been recently linked to brain signaling, the specific details of their role in movement disorders are still largely unknown and are being explored in this novel approach.
Where this research is happening
AUGUSTA, UNITED STATES
- AUGUSTA UNIVERSITY — AUGUSTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MUNTEAN, BRIAN S — AUGUSTA UNIVERSITY
- Study coordinator: MUNTEAN, BRIAN S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.