Understanding brain signals across time and frequency to better treat brain disorders
Official title: CRCNS: Investigating how neural dynamics transition along the time-frequency axis across scales
Funded at University of California Riverside · NIH-11416642 · Data updated 2026-11-12
A neuroscience grant aims to develop new ways to analyze brain activity across time and frequency to better understand and treat neurological and mental disorders.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Riverside NIH-funded |
| Lab location | 1 site (Riverside, United States) |
| Project start | September 15, 2025 |
| Project end | August 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $334,497 |
| NIH project number | 5R01NS148491-02 |
| Project ID | NIH-11416642 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with neurological or mental health disorders who could benefit from more precise brain-based therapies or diagnostic tools in the future.
✕Less likely to help
Healthy individuals may participate indirectly through baseline data but are not the target for therapeutic benefit.
What this research studies
This project will develop methods to uncover how brain signals change across different time and frequency scales. Researchers will combine mathematical analysis, algorithm design, computer simulations, and real brain data from electrophysiology and calcium imaging to test a central hypothesis about when these causal mechanisms are most detectable. The work is framed to connect complex brain dynamics with potential future therapeutic approaches, moving beyond single-scale analyses. If successful, these methods could help tailor interventions by revealing how brain networks interact under different conditions.
Why it matters
Potential benefit: Could lead to more accurate brain-behavior models that inform new treatments for neurological and mental health disorders.
How similar studies have gone: Previous work shows promise in linking time- and frequency-domain brain analyses, but integrating both scales remains a developing area.
Where this research is happening
-
University of California Riverside
Riverside, United States Active
Researchers
- Principal investigator: Nozari, Erfan — University of California Riverside
- Study coordinator: Nozari, Erfan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.