Understanding Brain Scans in Children with Neurodevelopmental Conditions
Radiomics for Clinically-Acquired Brain MRIs of Youth with Neurodevelopmental Disorders
This project aims to learn more about brain development in children with conditions like autism by looking closely at their existing brain MRI scans.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11134555 on NIH RePORTER |
What this research studies
We are using a new way to analyze brain MRI scans that children have already received during their regular medical care. This approach helps us compare individual brain measurements, like the size of different brain areas, against what is typical for children of the same age. By doing this, we hope to find subtle patterns in brain structure that might be linked to neurodevelopmental conditions. This work could help us better understand how these conditions affect the brain and potentially lead to new ways to help children in the future.
Who could benefit from this research
Good fit: This project focuses on brain MRI data from children aged 0-11 years old who have neurodevelopmental symptoms, such as those with autistic disorder.
Not a fit: Patients whose brain MRIs do not show neurodevelopmental symptoms or who are outside the 0-11 age range may not directly benefit from the findings of this specific analysis.
Why it matters
Potential benefit: If successful, this work could lead to a better understanding of brain differences in neurodevelopmental conditions, potentially aiding in earlier identification or more personalized care approaches.
How similar studies have performed: The research builds upon the team's prior success in developing brain growth charts from large neuroimaging datasets, indicating a foundation of established methodology.
Where this research is happening
Philadelphia, United States
- Children's Hosp of Philadelphia — Philadelphia, United States (Active)
Researchers
- Principal investigator: Alexander-Bloch, Aaron Felix — Children's Hosp of Philadelphia
- Study coordinator: Alexander-Bloch, Aaron Felix
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.