Understanding Brain Repair After Stroke
Integrating TPM and PAM to examine the metabolic underpinning of neurovascular repair after stroke
This work aims to better understand how the brain repairs itself and its blood vessels after a stroke, which could lead to new ways to help people recover.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-11128653 on NIH RePORTER |
What this research studies
Many people experience lasting challenges after a stroke because the brain's natural repair processes are not fully understood. This project uses advanced imaging techniques to look closely at how brain cells and blood vessels work together to heal after a stroke. By combining two powerful imaging methods, researchers can see how the brain reorganizes itself and how oxygen is used during recovery. This detailed view will help us learn more about the brain's own ability to mend itself.
Who could benefit from this research
Good fit: This foundational research is not directly recruiting patients but aims to benefit anyone who has experienced a stroke and is seeking better recovery options.
Not a fit: Patients currently seeking immediate treatment or direct clinical intervention would not receive direct benefit from this basic science project.
Why it matters
Potential benefit: If successful, this work could uncover new targets for therapies that improve brain repair and recovery for stroke survivors.
How similar studies have performed: While the specific dual-modal imaging technique is novel, other studies have shown that understanding neurovascular remodeling is crucial for stroke recovery.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Hu, Song — Washington University
- Study coordinator: Hu, Song
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.