Understanding Brain Regions in Decision-Making and Behavior
THE ROLE OF PREFRONTAL REGIONS IN ECONOMIC CHOICE AND CHOICE-GUIDED BEHAVIOR
['FUNDING_R01'] · WASHINGTON UNIVERSITY · NIH-11177938
This work explores how different parts of the brain help us make choices, especially when these choices are affected by conditions like depression or addiction.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-11177938 on ClinicalTrials.gov |
What this research studies
Our daily choices, like what to eat or how to act, can be disrupted in conditions such as frontotemporal dementia, major depression, and drug addiction. This project aims to uncover how the brain supports these decisions, focusing on areas like the orbitofrontal cortex. By understanding the brain's decision-making circuits, we hope to find new ways to help people whose choices are impacted by neurological and mental health challenges. This knowledge could eventually lead to better treatments and support for these conditions.
Who could benefit from this research
Good fit: This foundational research is not directly recruiting patients, but future clinical applications may benefit individuals with frontotemporal dementia, major depression, or drug addiction.
Not a fit: Patients without neurological or mental disorders affecting economic choice behavior may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could provide a foundational understanding of brain function that leads to new strategies for treating neurological and mental disorders affecting decision-making.
How similar studies have performed: Previous work has made considerable progress in linking brain regions like the orbitofrontal cortex to decision-making processes, suggesting a promising foundation for this research.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: PADOA-SCHIOPPA, CAMILLO — WASHINGTON UNIVERSITY
- Study coordinator: PADOA-SCHIOPPA, CAMILLO
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.