Understanding brain processes in psychosis to develop targeted treatments

Dysfunctional State Representations in Psychosis: From Neurophysiology to Neuroplasticity-based Treatment

NIH-funded research University of Minnesota · NIH-11109958

This study is looking at how the brains of people with psychosis work and how they process information, with the goal of finding better, personalized treatments to help improve their lives.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Minnesota NIH-funded
Lab location1 site (Minneapolis, United States)
Project IDNIH-11109958 on NIH RePORTER

What this research studies

This research investigates how the brain represents and processes information in individuals with psychosis. By using advanced computational models and studying both animal and human subjects, the project aims to identify the neural mechanisms that lead to disruptions in state representation. The findings could help in developing precision treatments tailored to individual cognitive profiles, potentially improving outcomes for those affected by psychosis.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with psychosis spectrum disorders.

Not a fit: Patients with psychosis who do not have measurable disruptions in state representation may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective, personalized treatments for individuals with psychosis.

How similar studies have performed: Previous research has shown promise in understanding cognitive disruptions in psychosis, suggesting that this approach could yield valuable insights.

Where this research is happening

Minneapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.