Understanding brain patterns in opioid use disorder treatment
Official title: Longitudinal neural fingerprinting of opioid-use trajectories
Funded at Yale University · NIH-10934369 · Data updated 2026-11-12
This study is looking at how your unique brain patterns can affect how well you respond to medication for opioid use disorder, with the goal of finding better, personalized treatment options just for you.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 30, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $209,375 |
| NIH project number | 5R21DA058415-02 |
| Project ID | NIH-10934369 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals currently receiving medications for opioid use disorder and are willing to participate in neuroimaging assessments.
✕Less likely to help
Patients who are not currently receiving treatment for opioid use disorder or those who have not been diagnosed with the condition may not benefit from this research.
What this research studies
This research investigates how individual brain patterns relate to treatment outcomes in people receiving medications for opioid use disorder (OUD). By using advanced neuroimaging techniques, the study aims to identify specific neural mechanisms that influence recovery and relapse. The approach focuses on personalized brain data rather than comparing groups, which may lead to more effective treatment strategies tailored to individual needs. Participants will be monitored over time to track changes in their brain activity and treatment responses.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment options for individuals struggling with opioid use disorder.
How similar studies have gone: Other research has shown promise in using personalized neuroimaging approaches to improve treatment outcomes in addiction, suggesting this method could be effective.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Yip, Sarah — Yale University
- Study coordinator: Yip, Sarah
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.