Understanding brain patterns in opioid use disorder treatment

Longitudinal neural fingerprinting of opioid-use trajectories

NIH-funded research Yale University · NIH-10934369

This study is looking at how your unique brain patterns can affect how well you respond to medication for opioid use disorder, with the goal of finding better, personalized treatment options just for you.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-10934369 on NIH RePORTER

What this research studies

This research investigates how individual brain patterns relate to treatment outcomes in people receiving medications for opioid use disorder (OUD). By using advanced neuroimaging techniques, the study aims to identify specific neural mechanisms that influence recovery and relapse. The approach focuses on personalized brain data rather than comparing groups, which may lead to more effective treatment strategies tailored to individual needs. Participants will be monitored over time to track changes in their brain activity and treatment responses.

Who could benefit from this research

Good fit: Ideal candidates are individuals currently receiving medications for opioid use disorder and are willing to participate in neuroimaging assessments.

Not a fit: Patients who are not currently receiving treatment for opioid use disorder or those who have not been diagnosed with the condition may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more personalized and effective treatment options for individuals struggling with opioid use disorder.

How similar studies have performed: Other research has shown promise in using personalized neuroimaging approaches to improve treatment outcomes in addiction, suggesting this method could be effective.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.