Understanding brain networks to improve mental health in young people

Personalized Functional Network Modeling to Characterize and Predict Psychopathology in Youth

NIH-funded research University of Pennsylvania · NIH-10827913

This study is looking at how young people's brains connect and work together, and how problems in these connections might relate to mental health issues like anxiety and depression, with the goal of creating better ways to diagnose and treat these conditions.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10827913 on NIH RePORTER

What this research studies

This research investigates how the brain's functional networks develop in youth and how abnormalities in these networks can be linked to mental health issues. By using advanced magnetic resonance imaging (MRI) techniques, the study aims to create personalized models of brain connectivity that can help identify specific mental health conditions. The approach combines large-scale neuroimaging data with innovative analytical methods to enhance the accuracy of diagnoses and tailor treatments for individuals. This could lead to more effective interventions for conditions like anxiety and depression in young people.

Who could benefit from this research

Good fit: Ideal candidates for this research include young individuals experiencing symptoms of mental health disorders such as anxiety or depression.

Not a fit: Patients who are not experiencing any mental health issues or who are outside the youth age range may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to personalized diagnostic tools and treatments for mental health disorders in youth.

How similar studies have performed: Previous research has shown promise in using personalized brain network models for understanding mental health, indicating that this approach could be effective.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.