Understanding brain networks that control behavior in Parkinson's disease
Investigating Inhibitory Control Networks in Parkinson's Disease
This study is looking at how certain parts of the brain affect thinking skills in people with Parkinson's disease, and it aims to find new ways to help improve memory and other cognitive abilities through special brain stimulation techniques.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Alabama at Birmingham NIH-funded |
| Lab location | 1 site (Birmingham, United States) |
| Project ID | NIH-11052472 on NIH RePORTER |
What this research studies
This research investigates how specific brain regions, particularly the dorsolateral prefrontal cortex, affect cognitive functions in patients with Parkinson's disease. By using advanced techniques during awake deep brain stimulation surgery, researchers will record brain activity to understand how these networks operate and how they can be influenced to improve cognitive symptoms. The goal is to identify new ways to enhance cognitive function in patients who often experience significant cognitive decline as their disease progresses. This study aims to develop effective neuromodulation strategies that could lead to better treatment options for cognitive impairments associated with Parkinson's disease.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Parkinson's disease who are experiencing cognitive impairments.
Not a fit: Patients without a diagnosis of Parkinson's disease or those who do not exhibit cognitive symptoms may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve cognitive function in patients with Parkinson's disease.
How similar studies have performed: Previous research has shown promise in using neuromodulation techniques to improve cognitive functions in various neurological conditions, suggesting potential success for this approach in Parkinson's disease.
Where this research is happening
Birmingham, United States
- University of Alabama at Birmingham — Birmingham, United States (Active)
Researchers
- Principal investigator: Bentley, Jessica Nicole — University of Alabama at Birmingham
- Study coordinator: Bentley, Jessica Nicole
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.