Understanding brain networks involved in high-level thinking and behavior

Thalamocortical cognitive networks in the healthy human brain

NIH-funded research Princeton University · NIH-11079576

This study is looking at how certain parts of the brain help us think and behave in everyday life, focusing on healthy adults, and it will also compare these findings to how the brain works in people with schizophrenia to better understand any differences.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionPrinceton University NIH-funded
Lab location1 site (Princeton, UNITED STATES)
Project IDNIH-11079576 on NIH RePORTER

What this research studies

This research investigates the roles of specific brain regions, the pulvinar and mediodorsal nuclei, in coordinating cognitive functions and behaviors in healthy adults. Using advanced imaging techniques like whole-brain fMRI, the study aims to map how these regions interact with other parts of the brain during complex tasks. By comparing these interactions with those observed in individuals with schizophrenia, the research seeks to uncover potential dysfunctions in cognitive processing. The project also incorporates animal models to enhance understanding of these brain networks across different species.

Who could benefit from this research

Good fit: Ideal candidates for this research are healthy adults aged 21 and older who are interested in contributing to our understanding of cognitive functions.

Not a fit: Patients with severe cognitive impairments or neurological disorders may not benefit directly from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment of cognitive disorders by identifying key brain network functions.

How similar studies have performed: Previous research has shown success in using fMRI to study brain networks, making this approach both validated and promising.

Where this research is happening

Princeton, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.